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Evaluation of analgesic activity of P. domestica L.

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dc.contributor.author Zahra Yaqeen
dc.contributor.author Naqvi, Naim-ul-Hassan
dc.contributor.author Hina Imran
dc.contributor.author Nudrat Fatima
dc.contributor.author Tehmina Sohail
dc.contributor.author Zakir-ur-Rehman
dc.contributor.author Atiq-ur-Rahman
dc.date.accessioned 2023-01-19T10:43:35Z
dc.date.available 2023-01-19T10:43:35Z
dc.date.issued 2017-07-20
dc.identifier.citation Yaqeen, Z., Naqvi, N. U. H., Imran, H., Fatima, N., & Sohail, T. (2013). Evaluation of analgesic activity of P. domestica L. Pakistan Journal of Pharmaceutical Sciences, 26(1). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16121
dc.description.abstract This research study was conducted to investigate acute oral toxicity and analgesic activity of ethanol extract of P. domestica fruit by using tail flick analgesiometer at 300 and 500mg/kg doses in animal models. Acute oral toxicity results showed that crude extract is safe up to the dose of 5g/kg body weight of animals. The analgesic activity revealed that P. domestica extract at 500mg/kg dose possesses highest significant and prolonged analgesic activity in dose dependent manner as compared to standard and control groups. Aspirin 300mg/kg body weight was used as standard drug. Phytochemical analysis was also carried out which showed the presence of certain phytochemicals constituents in test drug that are responsible for analgesic activity. Therefore the results are justified. en_US
dc.language.iso en en_US
dc.publisher Karachi: Pakistan Botanical Society, University of Karachi en_US
dc.subject P. domestica fruit en_US
dc.subject acute oral toxicity en_US
dc.subject analgesic activity en_US
dc.subject rats and mice. en_US
dc.title Evaluation of analgesic activity of P. domestica L. en_US
dc.type Article en_US


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