dc.contributor.author |
Guiming Fu |
|
dc.contributor.author |
Huoyan Tong |
|
dc.contributor.author |
Hailong Zeng |
|
dc.contributor.author |
Bin Zou |
|
dc.contributor.author |
Jianxin Chai |
|
dc.contributor.author |
Lunning Zhang |
|
dc.contributor.author |
Mingyong Xie |
|
dc.contributor.author |
Feng Chen |
|
dc.contributor.author |
Yin Wan |
|
dc.date.accessioned |
2023-01-20T05:08:03Z |
|
dc.date.available |
2023-01-20T05:08:03Z |
|
dc.date.issued |
2018-07-20 |
|
dc.identifier.citation |
Guiming, F., Huoyan, T., Hailong, Z., Bin, Z., Jianxin, C., Lunning, Z., ... & Yin, W. (2018). Antioxidant and xanthine oxidase inhibitory activity of Eucommia ulmoides oliver leaf extracts. |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/16173 |
|
dc.description.abstract |
The total phenolic content, flavonoid content, in vitro xanthine oxidase (XOD) inhibitory activity and antioxidant activity (AA) of Eucommia ulmoides Oliver leaf extracts were investigated. The AA investigations included 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, β-carotene/linoleic acid bleaching assay and oxygen radical absorbance capacity (ORAC) test. The ethyl acetate fraction (EE) showed the highest AA and xanthine oxidase inhibitory activity. Whilst the lowest 50% inhibition (IC50) value of this fraction for DPPH free radical scavenging was 0.045mg/mL, its highest ORAC value was 10.57 µmol TE/mg. The highest inhibition rate against linoleic acid oxidation observed was 69.41%, and the lowest IC50 value for xanthine oxidase activity inhibition was 2.47mg/mL. These results show that E. ulmoides leaf extract is a promising source of natural antioxidants because it contains high contents of bioactive compounds, including chlorogenic acid, rutin, hyperin and astragalin, as detected by high-performance liquid chromatography coupled to HPLC-DAD-ESI-MS. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Pakistan Botanical Society, University of Karachi |
en_US |
dc.subject |
E. ulmoides leaf extracts |
en_US |
dc.subject |
total phenolics |
en_US |
dc.subject |
total flavonoids |
en_US |
dc.subject |
antioxidant activity |
en_US |
dc.subject |
xanthine oxidase inhibitory activity. |
en_US |
dc.title |
Antioxidant and xanthine oxidase inhibitory activity of Eucommia ulmoides Oliver leaf extracts |
en_US |
dc.type |
Article |
en_US |