PASTIC Dspace Repository

Antioxidant and xanthine oxidase inhibitory activity of Eucommia ulmoides Oliver leaf extracts

Show simple item record

dc.contributor.author Guiming Fu
dc.contributor.author Huoyan Tong
dc.contributor.author Hailong Zeng
dc.contributor.author Bin Zou
dc.contributor.author Jianxin Chai
dc.contributor.author Lunning Zhang
dc.contributor.author Mingyong Xie
dc.contributor.author Feng Chen
dc.contributor.author Yin Wan
dc.date.accessioned 2023-01-20T05:08:03Z
dc.date.available 2023-01-20T05:08:03Z
dc.date.issued 2018-07-20
dc.identifier.citation Guiming, F., Huoyan, T., Hailong, Z., Bin, Z., Jianxin, C., Lunning, Z., ... & Yin, W. (2018). Antioxidant and xanthine oxidase inhibitory activity of Eucommia ulmoides oliver leaf extracts. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16173
dc.description.abstract The total phenolic content, flavonoid content, in vitro xanthine oxidase (XOD) inhibitory activity and antioxidant activity (AA) of Eucommia ulmoides Oliver leaf extracts were investigated. The AA investigations included 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, β-carotene/linoleic acid bleaching assay and oxygen radical absorbance capacity (ORAC) test. The ethyl acetate fraction (EE) showed the highest AA and xanthine oxidase inhibitory activity. Whilst the lowest 50% inhibition (IC50) value of this fraction for DPPH free radical scavenging was 0.045mg/mL, its highest ORAC value was 10.57 µmol TE/mg. The highest inhibition rate against linoleic acid oxidation observed was 69.41%, and the lowest IC50 value for xanthine oxidase activity inhibition was 2.47mg/mL. These results show that E. ulmoides leaf extract is a promising source of natural antioxidants because it contains high contents of bioactive compounds, including chlorogenic acid, rutin, hyperin and astragalin, as detected by high-performance liquid chromatography coupled to HPLC-DAD-ESI-MS. en_US
dc.language.iso en en_US
dc.publisher Karachi: Pakistan Botanical Society, University of Karachi en_US
dc.subject E. ulmoides leaf extracts en_US
dc.subject total phenolics en_US
dc.subject total flavonoids en_US
dc.subject antioxidant activity en_US
dc.subject xanthine oxidase inhibitory activity. en_US
dc.title Antioxidant and xanthine oxidase inhibitory activity of Eucommia ulmoides Oliver leaf extracts en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account