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The effect of hydro alcoholic extract of Juglans regia leaves in streptozotocin-nicotinamide induced diabetic rats

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dc.contributor.author Jamshid Mohammadi
dc.contributor.author Delaviz, Hamdollah
dc.contributor.author Roozbehi, Amrollah
dc.date.accessioned 2023-01-20T05:17:55Z
dc.date.available 2023-01-20T05:17:55Z
dc.date.issued 2012-04-19
dc.identifier.citation Mohammadi, J., Delaviz, H., Malekzadeh, J. M., & Roozbehi, A. (2012). The effect of hydro alcoholic extract of Juglans regia leaves in streptozotocin-nicotinamide induced diabetic rats. Pak J Pharm Sci, 25(2), 407-411. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16187
dc.description.abstract Phytotherapy has been achieved to maintain glycemic control in patients with diabetes mellitus. The present study was conducted to evaluate the antihyperglycemic properties of the Juglans regia leaf extract in streptozotocinnicotinamide induced diabetic rats. Nicotinamide was injected intraperitonealy (i.p.) 15 min before the injection of Streptozotocin (i.p.). One week after induction of diabetes, oral treatment started with extract of Juglans regia and Metformin and continued for 4 weeks. Fasting blood sugar, body weight, serum lipids and insulin level were measured in different groups. A significant reduction of glucose, HbA1c, total cholesterol and serum triglycerides were detected after 4 weeks in rats treated with Juglans regia leaves compared to the control groups. Thus, Juglans regia extract treatment showed potential hypoglycemic and hypolipidemic effects in type 2 diabetic rats. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Juglans regia en_US
dc.subject glucose en_US
dc.subject serum lipids en_US
dc.subject Streptozotocin en_US
dc.subject Nicotinamide en_US
dc.subject type 2 diabetes en_US
dc.title The effect of hydro alcoholic extract of Juglans regia leaves in streptozotocin-nicotinamide induced diabetic rats en_US
dc.type Article en_US


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