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Correction of iron deficiency anemia in pregnancy and its effects on Superoxide dismutase

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dc.contributor.author Shamaila Khalid
dc.contributor.author Syed Iqbal Ahmad
dc.date.accessioned 2023-01-20T05:20:00Z
dc.date.available 2023-01-20T05:20:00Z
dc.date.issued 2012-04-21
dc.identifier.citation Khalid, S., & Ahmad, S. I. (2012). Correction of iron deficiency anemia in pregnancy and its effects on Superoxide dismutase. Pakistan Journal of Pharmaceutical Sciences, 25(2). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16192
dc.description.abstract Iron deficiency anemia (IDA) affects not only the hematological parameters but also disturb the oxidative balance of body. In pregnancy, this is much more considerable as oxidative stress is considered to be one of the physiological changes during this period. This study aims to observe the effect of daily iron supplement on oxidative stress in pregnancy. In this study, 30 pregnant women with IDA were treated with daily oral iron supplements for 12 weeks. After 12 weeks hemoglobin (Hb), hematocrit, serum ferritin concentration (SFC) and superoxide dismutase (SOD) activity were measured and compared with pre-supplement levels. A significant increase in all the parameters was observed after treatment (p<0.05). When post supplemental values of SFC and SOD were compared with control group comprising of 10 non anemic pregnant women, they were significantly low (p<0.05). Our results indicate that oxidative stress in pregnancy associated with IDA decreases with daily iron supplements but fail to reach normal pregnant levels. This supports iron over load theory in daily iron supplements and suggests that oxidative stress increases if pregnancy is associated with iron deficiency. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Iron deficiency en_US
dc.subject anemia en_US
dc.subject oxidative stress en_US
dc.subject pregnancy en_US
dc.subject superoxide dismutase en_US
dc.title Correction of iron deficiency anemia in pregnancy and its effects on Superoxide dismutase en_US
dc.type Article en_US


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