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Study of surface activity of piroxicam at the interface of palm oil esters and various aqueous phases

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dc.contributor.author Abdulkarim, Muthanna Fawzy
dc.contributor.author Ghassan Zuhair Abdullah
dc.contributor.author Chitneni
dc.contributor.author Yam, Mun Fei
dc.contributor.author Mahdi, Elrashid Saleh
dc.contributor.author Ibrahim Muhammad Salman
dc.contributor.author Omar Ziad Ameer
dc.contributor.author Munavvar Abdul Sattar
dc.contributor.author Mahiran Basri
dc.contributor.author Azmin Mohd Noor
dc.date.accessioned 2023-01-20T05:20:20Z
dc.date.available 2023-01-20T05:20:20Z
dc.date.issued 2012-04-22
dc.identifier.citation Abdulkarim, M. F., Abdullah, G. Z., Chitneni, M., Yam, M. F., Mahdi, E. S., Salman, I. M., ... & Noor, A. M. (2012). Study of surface activity of piroxicam at the interface of palm oil esters and various aqueous phases. Pakistan Journal of Pharmaceutical Sciences, 25(2), 429-433. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16193
dc.description.abstract The surface activity of some non-steroidal anti-inflammatory agents like ibuprofen was investigated extensively. This fact has attracted the researchers to extend this behavior to other agents like piroxicam. Piroxicam molecules are expected to orient at the interface of oil and aqueous phase. The aim of this study was, firstly, to assess the surface and interfacial tension behaviour of newly synthesised palm oil esters and various pH phosphate buffers. Furthermore, the surface and interfacial tension activity of piroxicam was studied. All the measurements of surface and interfacial tension were made using the tensiometer. The study revealed that piroxicam has no effect on surface tension values of all pH phosphate buffers and palm oil esters. Similarly, various concentrations of piroxicam did not affect the interfacial tensions between the oil phase and the buffer phases. Accordingly, the interfacial tension values of all mixtures of oil and phosphate buffers were considerably high which indicates the immiscibility. It could be concluded that piroxicam has no surface activity. Additionally, there is no surface pressure activity of piroxicam at the interface of plam oil esters and phosphate buffers in the presence of Tweens and Spans. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Surface activity en_US
dc.subject palm oil esters en_US
dc.subject hosphate buffers en_US
dc.subject piroxicam en_US
dc.title Study of surface activity of piroxicam at the interface of palm oil esters and various aqueous phases en_US
dc.type Article en_US


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