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Antioxidant, cytotoxicity, protein kinase inhibition and antibacterial activities of Fragaria × ananassa leaves

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dc.contributor.author Ihsan Khan
dc.contributor.author Saira Tabassum
dc.contributor.author Tofeeq-ur-Rehman
dc.contributor.author Muhammad Ikram
dc.contributor.author Ihsan ul Haq
dc.contributor.author Muhammad Zia
dc.date.accessioned 2023-01-20T05:45:24Z
dc.date.available 2023-01-20T05:45:24Z
dc.date.issued 2018-07-20
dc.identifier.citation Khan, I., Tabassum, S., Ikram, M., & Zia, M. (2018). Antioxidant, cytotoxicity, protein kinase inhibition and antibacterial activities of Fragaria× ananassa leaves. Pakistan Journal of Pharmaceutical Sciences, 31(4). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16199
dc.description.abstract Fragaria × ananassa leaves extracts prepared in different solvents were subject for antioxidative, cytotoxicity, protein kinase inhibition and antibacterial activities. The extracts showed varying activities depending upon solvent used for extraction. Combined effect of methanol and ethyl acetate showed maximum antioxidant and reducing power potential (207.65±6µg AAE/mg and 88.58±20µg AAE/mg, respectively). Maximum DPPH (2,2-diphenyl-1-picryl hydrazyl) free radical scavenging activity was calculated by when methanol: chloroform and acetate fractions were used (87.68% and 86.88% inhibition, respectively). Total phenolics varied from 186 to 1.91µg AAE/mg while total flavonoids also significantly varied among the extracts. The extracts also showed significant activities against brine shrimp larvae and bacterial strains tested. The study concludes that Fragaria × ananassa leaves can be a good source for isolation of active phytochemicals to be used in different industries. en_US
dc.language.iso en en_US
dc.publisher Karachi: Pakistan Botanical Society, University of Karachi en_US
dc.subject Fragaria × ananassa leaves extracts en_US
dc.subject antioxidant en_US
dc.subject DPPH, antibacterial en_US
dc.subject protein kinase, cytotoxicity en_US
dc.title Antioxidant, cytotoxicity, protein kinase inhibition and antibacterial activities of Fragaria × ananassa leaves en_US
dc.type Article en_US


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