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Antihyperglycemic effect of Conocarpus erectus leaf extract in alloxaninduced diabetic mice

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dc.contributor.author Syed Ali Raza
dc.contributor.author Chaudhary, Ayoub Rashid
dc.contributor.author Muhammad Waseem Mumtaz
dc.contributor.author Abdul Ghaffar
dc.contributor.author Ahmad Adnan
dc.contributor.author Abdul Waheed
dc.date.accessioned 2023-01-20T06:52:16Z
dc.date.available 2023-01-20T06:52:16Z
dc.date.issued 2018-03-06
dc.identifier.citation Raza, S. A., Chaudhary, A. R., Mumtaz, M. W., Ghaffar, A., Adnan, A., & Waheed, A. (2018). Antihyperglycemic effect of Conocarpus erectus leaf extract in alloxan-induced diabetic mice. Pakistan journal of pharmaceutical sciences, 31. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16298
dc.description.abstract Synthetic drugs have widely been helpful in management of diabetes mellitus type 2. However, side effects associated with synthetic drugs serve as an impetus to explore plants as alternate mode of treatment. The hydroethanolic leaf extracts of Conocarpus erectus were evaluated for phenolic contents, flavonoid distribution, antioxidant activity and antidiabetic potential. The maximum extract yield, total phenolic and flavonoid contents were exposed by 60% ethanolic extract. The Antioxidant and anti α-glucosidase tendency of 60% ethanolic extract was the most promising and complemented by in-vivo antihyperglycemic impact on mice. The findings were substantial regarding suppression of blood glucose levels in alloxan induced diabetic mice establishing the Conocarpus erectus as proficient pool of nutraceuticals for diabetes mellitus type 2 management. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Freeze drying en_US
dc.subject phytochemical en_US
dc.subject antioxidant en_US
dc.subject antidiabetic en_US
dc.subject Conocarpus erectus en_US
dc.title Antihyperglycemic effect of Conocarpus erectus leaf extract in alloxaninduced diabetic mice en_US
dc.type Article en_US


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