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Antioxidant capacity and polyphenolic content of the Echinocystis lobata (Michx.) Torr. et A.Gray flowers

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dc.contributor.author Ielciu, Irina
dc.contributor.author Hanganu, Daniela
dc.contributor.author Păltinean, Ramona
dc.contributor.author Vlase, Laurian
dc.contributor.author Frédérich, Michel
dc.contributor.author Gheldiu, Ana-Maria
dc.contributor.author Benedec, Daniela
dc.contributor.author Crişan, Gianina
dc.date.accessioned 2023-01-20T06:55:12Z
dc.date.available 2023-01-20T06:55:12Z
dc.date.issued 2018-03-12
dc.identifier.citation Ielciu, I., Hanganu, D., Ramona, P., Vlase, L., Frederich, M., Gheldiu, A. M., ... & Cri, G. (2018). Antioxidant capacity and polyphenolic content of the Echinocystis lobata (Michx.) Torr. et A. Gray flowers. Pakistan Journal of Pharmaceutical Sciences, 31(2). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16306
dc.description.abstract Echinocystis lobata (Michx.) Torr. et A.Gray is a spontaneous species in the Romanian flora, lesser studied by scientific literature, but which has proved significant activities in traditional medicine. The present study is aimed to provide data on the polyphenolic compounds in the composition of the flowers of this species and to test their biological potential. Polyphenols were identified and quantified using an HPLC-MS method. Tested biological activities were the cytotoxic, anti-plasmodial and antioxidant ones. Methods used for testing the antioxidant activity were the DPPH, CUPRAC, FRAP, TEAC, EPR and SNPAC assays. Cytotoxic activity was tested on cancerous and healthy cell lines and anti-plasmodial activity was assesed on two strains of Plasmodium falciparum. Ethanolic extracts of the flowers of E. lobata proved to contain isoquercitrin, rutin, quercitrin, kaempferol, p-coumaric and ferulic acid. No cytotoxic and antiplasmodial activity was found, but antioxidant assays showed an important antioxidant capacity. The obtained results show that flowers of E. lobata are important sources of antioxidant compounds. It is the first approach of the kind on the flowers of this species and it offers a new perspective on possible sources of antioxidant compounds. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Echinocystis lobata (Michx.) Torr en_US
dc.subject et A.Gray en_US
dc.subject polyphenols en_US
dc.subject antioxidant en_US
dc.title Antioxidant capacity and polyphenolic content of the Echinocystis lobata (Michx.) Torr. et A.Gray flowers en_US
dc.type Article en_US


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