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Drug utilization and prescribing pattern of antibiotics in a tertiary care setups; trends and practices

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dc.contributor.author Huma Ali
dc.contributor.author Farya Zafar
dc.contributor.author Shazia Alam
dc.contributor.author Anwar Ejaz Beg
dc.contributor.author Rabia Bushra
dc.contributor.author Ammara Manzoor
dc.contributor.author Ghazala R Naqvi
dc.contributor.author Riffat Yasmeen
dc.contributor.author Yousra Shafiq
dc.contributor.author Anum Tariq
dc.contributor.author Saba Zubair
dc.contributor.author Saima Saleem
dc.date.accessioned 2023-01-20T06:55:31Z
dc.date.available 2023-01-20T06:55:31Z
dc.date.issued 2018-03-14
dc.identifier.citation Ali, H., Zafar, F., Alam, S., Beg, A. E., Bushra, R., Manzoor, A., ... & Saleem, S. (2018). Drug utilization and prescribing pattern of antibiotics in a tertiary care setups; trends and practices. Pakistan journal of pharmaceutical sciences, 31. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16307
dc.description.abstract Irrational, over and misuse of antibiotics arise as global concern in both hospital and community settings and lead to adverse events including antimicrobial resistance, associated health problems, amplified hospitalization stay and cost. Hence, Drug Utilization Evaluation (DUE) studies are designed to evaluate and improve the prescribing, administration and the rational use of medications. The present study was designed to assess the pattern of antimicrobial drug utilization in in-patients cohort of tertiary care setup in Karachi, Pakistan. This cross sectional observational study was conducted in retrospective manner. World health organization (WHO) guidelines and criteria are considered to evaluate the appropriateness of drug use in various disease conditions. ATC/DDD system was applied to determine the study outcome. High frequency of antibiotics utilization found in respiratory tract infections of both lower (LRTI) 16.8% (n=42) and upper (UTI) 13.2% (n=33). The estimated total number of drug units administered per month was greater with cefixime (46) and ciprofloxacin (45) both. DDD/100 bed days drug utilization of antibiotics was higher with ciprofloxacin, cefexime and meropenem (47, 46 and 29.25) correspondingly. In conclusion, the current investigation signifies extensive scope for progress in prescribing trend. Drug adherence to customary guidelines of disease management and constraint policies to endorse judicious drug use may be considered vital in healthcare Setup. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Drug Utilization Evaluation en_US
dc.subject ATC/DDD system en_US
dc.subject retrospective en_US
dc.subject compliance en_US
dc.subject WHO guidelines en_US
dc.title Drug utilization and prescribing pattern of antibiotics in a tertiary care setups; trends and practices en_US
dc.type Article en_US


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