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Development and formulation of metformin (Antidiabetic) effervescent Granules: To increase patient compliance and its stability study

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dc.contributor.author Saeed Ur Rashid Nazir
dc.contributor.author Ghazala Ambreen
dc.contributor.author Hafiz Muhammad Irfan
dc.contributor.author Sajid Bashir
dc.contributor.author Asim Rauf
dc.date.accessioned 2023-01-20T07:11:37Z
dc.date.available 2023-01-20T07:11:37Z
dc.date.issued 2014-07-02
dc.identifier.citation Nazir, S. R., Ambreen, G., Irfan, H. M., Bashir, S., & Rauf, A. (2014). Development and formulation of metformin (Antidiabetic) effervescent Granules: to increase patient compliance and its stability study. Pak J Pharm Sci, 27(4), 763-766. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16355
dc.description.abstract Convenience of administration and patient compliance are gaining importance in the formulation of dosage forms. Many patients, like elderly people and person with dysphagia find difficulty to swallow the tablets and thus do not comply with prescriptions. So the present study was conducted to develop and formulate metformin effervescent granules. The stability study was carried out for 24 weeks (168 days) at temperatures of 4˚C, Room temperature, 40˚C & 60˚C and at the end, the %age of drug remaining in the formulation was determined. The results showed that the formulation of metformin effervescent granules were remained best stable at 4˚C in refrigerator, as the %age of drug remaining is not decreased more than 5% and the formulation stored at room temperature, was also found to be very close to the standard at the end of 24 weeks. It is concluded from the study that granules may be another dosage form to use as antidiabetic pharmaceutical product. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy, University of Karachi en_US
dc.subject Stability en_US
dc.subject Metformin en_US
dc.subject effervescent granules en_US
dc.subject development en_US
dc.title Development and formulation of metformin (Antidiabetic) effervescent Granules: To increase patient compliance and its stability study en_US
dc.type Article en_US


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