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REPORT Comparison of qualitative, quantitative analysis and antioxidant potential between wild and cultivated Borago officinalis leaves from palestine

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dc.contributor.author Hassan Abu-Qaoud
dc.contributor.author Nuha Shawarb
dc.contributor.author Fatima Hussen
dc.contributor.author Nidal Jaradat
dc.contributor.author Munqez Shtaya
dc.date.accessioned 2023-01-20T07:13:51Z
dc.date.available 2023-01-20T07:13:51Z
dc.date.issued 2018-05-31
dc.identifier.citation Abu-Qaoud, H., Shawarb, N., Hussen, F., Jaradat, N., & Shtaya, M. (2018). Comparison of qualitative, quantitative analysis and antioxidant potential between wild and cultivated Borago officinalis leaves from palestine. Pakistan journal of pharmaceutical sciences, 31(3). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16363
dc.description.abstract Borago officinalis plant is an important plant of high medicinal and nutritional values. This study designed to evaluate antioxidant activity, screen the existence of phytogenic chemical compounds and to determine the total flavonoid and phenol contents of wild and cultivated Borago officinalis. Total flavonoid contents of the wild and cultivated Borago officinalis were determined by using rutin reference standard method and total phenols determined by using Folin Ciocalteu’s method while antioxidant activity evaluated by using 2, 2-diphenyl-1-picryl-hydrazyl-hydrate assay. Phytochemical analyses indicated the presence of carbohydrate, phenols, flavonoids, phytosteroids tannins and volatile oil. The total flavonoid content of the methanolic extract from the wild borage plant was 22.4mg RU/g this value was reduced to 13.1mg RU/g for the cultivated methanolic extract as well as the total phenols contents was dropped from 5.21mg GA/g to 2.37mg GA/g methanolic extracts. Total tannins content of the wild growing borage plant was 13.7mg GA/g methanolic extract. This value was higher in the cultivated borage with 21.33mg GA/g methanolic extract. The wild leaves extract had IC50 =6.3µg/mL for wild leaves extract was closer to IC50 value of Trolox (standard reference with high antioxidant activity), while the cultivated leaves extract had higher IC50= 8.7µg/ml which mean lower antioxidant activity than the wild growing one. The data of this study showed that the extracts of Borago officinalis possess antioxidant and free radical scavenging activities. Variation was clear between wild and cultivated species, these findings propose that such plant extract could have a wide range of applications in both food and pharmaceutical industries. Therefore, more research is necessary to investigate different cultural practices on the efficiency of borage plant. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Borago officinalis en_US
dc.subject phenols en_US
dc.subject flavonoids en_US
dc.subject tannins en_US
dc.subject antioxidants en_US
dc.title REPORT Comparison of qualitative, quantitative analysis and antioxidant potential between wild and cultivated Borago officinalis leaves from palestine en_US
dc.type Article en_US


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