PASTIC Dspace Repository

Cytotoxic activity of plants of family Zygophyllaceae and Euphorbiaceae

Show simple item record

dc.contributor.author Ghulam Dastagir
dc.contributor.author Farrukh Hussain
dc.date.accessioned 2023-01-20T07:19:59Z
dc.date.available 2023-01-20T07:19:59Z
dc.date.issued 2014-07-08
dc.identifier.citation Dastagir, G., & Hussain, F. (2014). Cytotoxic activity of plants of family Zygophyllaceae and Euphorbiaceae. Pakistan Journal of Pharmaceutical Sciences, 27(4). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16369
dc.description.abstract The methanolic and n-hexane extracts of studied plants showed significant toxicity to brine shrimps. The methanolic extract of Fagonia cretica had highest LD50 (117.72) value, while Peganum harmala showed low LD50 value (41.70) compared to n-hexane extract. The methanolic and n-hexane extracts of Tribulus terrestris showed similar LD50 values. The methanolic extract of Chrozophora tinctoria showed low LD50 value than the n-hexane extract. The methanolic extract of Ricinus communis showed highest LD50 value while the n-hexane extract showed lowest LD50 value. The LD50 value less than 100 was obtained for n-hexane extracts of Fagonia cretica, Peganum harmala and Ricinus communis. The n-hexane extracts of these plants also showed the highest toxicity as compare to methanolic extracts. The chemical constituents detected in the present investigation might be responsible for cytotoxic activity. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy, University of Karachi en_US
dc.subject Medicinal plants en_US
dc.subject cytotoxic activity en_US
dc.subject zygophyllaceae en_US
dc.subject euphorbiaceae en_US
dc.subject phytochemical en_US
dc.subject screening en_US
dc.title Cytotoxic activity of plants of family Zygophyllaceae and Euphorbiaceae en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account