dc.contributor.author | Madiha Moid | |
dc.contributor.author | Sidra Afzal | |
dc.contributor.author | Najia Rahim | |
dc.contributor.author | Tariq Ali | |
dc.contributor.author | Wajiha Iffat | |
dc.contributor.author | Lubna Bashir | |
dc.contributor.author | Shazia Naz | |
dc.date.accessioned | 2023-01-20T07:34:54Z | |
dc.date.available | 2023-01-20T07:34:54Z | |
dc.date.issued | 2018-07-18 | |
dc.identifier.citation | Moid, M., Afzal, S., Rahim, N., Ali, T., Iffat, W., Bashir, L., & Naz, S. (2018). High performance liquid chromatographic method validation for determination of rosuvastatin calcium in tablet dosage forms. Pak. J. Pharm. Sci, 31(4), 1577-1582. | en_US |
dc.identifier.issn | 1011-601X | |
dc.identifier.uri | http://142.54.178.187:9060/xmlui/handle/123456789/16412 | |
dc.description.abstract | A precise, sensitive and quick High Performance Liquid Chromatographic (HPLC) method for the determination of rosuvastatin calcium in bulk and tablet dosage forms has been validated. The chromatographic scheme involved: Sil-20A auto sampler, LC-20A pump, SPD-20A UV/visible detector with separation attained by C18 column at 40ºC temperature through a mobile phase of acetonitrile and buffer (50:50) at a flow rate of 1.0ml/min. The method is precise (%RSD for intra-day and inter-day extended between 1.06-1.54% and 0.103-1.78%) and linear (r2 =0.9997). Limit of detection and quantification (LOD & LOQ) of the adopted method were 0.78 and 1.56µg/ml. The proposed HPLC method was established to be sensitive, precise and swift that can be proficiently adopted in quality control/quality assurance laboratories for predictable investigation of the bulk and oral solid dosage forms of rosuvastatin calcium. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi | en_US |
dc.subject | Rosuvastatin calcium | en_US |
dc.subject | intra-day | en_US |
dc.subject | inter-day | en_US |
dc.title | High performance liquid chromatographic method validation for determination of rosuvastatin calcium in tablet dosage forms | en_US |
dc.type | Article | en_US |