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PHYTOCHEMICAL ANALYSIS, ANTIOXIDANT AND ANTIBACTERIAL EFFECTS OF SEA BUCKTHORN BERRIES

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dc.contributor.author SAADIA CHAMAN
dc.contributor.author SYED, NAWAZISH-I-HUSAIN
dc.contributor.author ZEESHAN DANISH
dc.contributor.author KHAN, FARRAKH ZIA
dc.date.accessioned 2023-01-20T07:36:56Z
dc.date.available 2023-01-20T07:36:56Z
dc.date.issued 2011-07-20
dc.identifier.citation Chaman, S., Syed, N. I., Danish, Z., & Khan, F. Z. (2011). Phytochemical analysis, antioxidant and antibacterial effects of sea buckthorn berries. Pakistan Journal of Pharmaceutical Sciences, 24(3). en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16419
dc.description.abstract Sea buckthorn berries are therapeutically used as folk medicine for a variety of diseases, however, the scientific evidence is hardly available to support their role. This study explored their chemical constituents and their role as antioxidant and antibacterial agents. Three common solvents such as petroleum ether (40º - 60ºC), chloroform and methanol were successively used for the extraction of active principles from sea buckthorn berries. Five major fractions (F1-F5) were isolated from the active methanol extract by column and thin layer chromatography. An attempt was made to identify the chemical nature of pooled fractions by available spectral means. Antioxidant potential of methanol extract and its fractions was measured by DPPH, formation of phosphomolybdenum complex and TBA methods. The hole-plate diffussion method was used to find out the antibacterial activity. A very brief structure-activity relationship of the potent antioxidant and antimicrobial compounds is discussed. Methanolic extract and its fractions contain numerous phenolic compounds such as flavonoids, which may be responsible for antioxidant and antibacterial effects. en_US
dc.language.iso en en_US
dc.publisher Karachi:Pakistan Journal of Pharmaceutical Sciences, university of Karachi. en_US
dc.subject Antibacterial en_US
dc.subject antioxidant en_US
dc.subject phytochemical en_US
dc.subject sea buckthorn en_US
dc.title PHYTOCHEMICAL ANALYSIS, ANTIOXIDANT AND ANTIBACTERIAL EFFECTS OF SEA BUCKTHORN BERRIES en_US
dc.type Article en_US


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