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ANTIOXIDANT ACTIVITY OF COVOLVULUS HYSTRIX VAHL AND ITS CHEMICAL CONSTITUENTS

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dc.contributor.author DONIA, ABD EL RAHEIM MOHAMMED
dc.contributor.author ALQASOUMI, SALEH IBRAHIM
dc.contributor.author AWAAD, AMANI SHAFEEK
dc.contributor.author CRACKER, LYLE
dc.date.accessioned 2023-01-20T07:40:16Z
dc.date.available 2023-01-20T07:40:16Z
dc.date.issued 2011-04-08
dc.identifier.citation ABD EL RAHEIM MOHAMMED, D. O. N. I. A., Alqasoumi, S. I., Awaad, A. S., & Cracker, L. (2011). Antioxidant activity of Covolvulus hystrix Vahl and its chemical constituents. Pak. J. Pharm. Sci, 24(2), 143-147. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16431
dc.description.abstract Total alcohol and successive extracts (diethyl ether, chloroform, ethyl acetate and n-butanol) of Covolvulus hystrix Vahl were screened for their antioxidant activity using free radical 2-2- diphenyl-1-picrylhydrazyl (DPPH) and Trolox as reference substance. The tested extracts showed variable antioxidant activities. The highest antioxidant activity was achieved in total alcohol (48.32%) followed by ethyl acetate (37. 8 %) and nbutanol (32.96 %) extracts. From the ethyl acetate extract four compounds were isolated and identified as quercetin, quercetin 3-0-rutinoside and quercetin-7-O-rhamnoside in addition to ferulic acid using different spectroscopic analysis such as, 1 HNMR, 13CNMR, COSY, HMBC and HMQC en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.subject Antioxidant activity en_US
dc.subject Convolvulus hystrix en_US
dc.subject flavonoids en_US
dc.subject ferulic acid en_US
dc.subject total phenolics en_US
dc.title ANTIOXIDANT ACTIVITY OF COVOLVULUS HYSTRIX VAHL AND ITS CHEMICAL CONSTITUENTS en_US
dc.type Article en_US


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