Abstract:
The objective of this study is to isolate and production of secondary metabolites with bioactive substances by
coral reef (Acropora formosa and Favia palida) associated bacteria was carried out from the Tuticorin coastal
waters, Southeastern India. The isolated coral associated bacteria were found to have an antagonistic effect
against 10 human pathogens. The pathogens were Escherichia coli, Shigella dysentriae, Staphylococcus
epidermidis, S. aureus, Klebsiella pneumoniae, Pseudomonas aerogenosa, Vibrio cholerae, Streptococcus
pneumoniae, S. faecalis and Bacillus cereus. It was observed that, out of the total 689 bacterial strains isolated, 10 and 13% of isolates from A. formosa and Favia palida, respectively were found to have antagonistic activity against the pathogens, A higher percentage of antagonistic strains were conferred from Favia palida with 13%. It was observed that all antagonistic strains were able to inhibit at least two of the human pathogens.
