Abstract:
The effect of ethanol root extract of H. africana on experimentally induced diarrhoea and ulcer was studied in
rodents. The extract (200 – 600mg/kg) considerably inhibited castor oil induced diarrhoea, small intestine
transit time and castor oil induced fluid accumulation as well as indomethacin and ethanol induced ulcer
models. The effect of the extract in these models was comparable to the various standard drugs used. The root extract of H. africana has antidiarrhoeal and antiulcer properties which justify its uses in ethnomedicine.
