dc.contributor.author |
Abdur Rauf |
|
dc.contributor.author |
Khan, Ajmal |
|
dc.contributor.author |
Nizam Uddin |
|
dc.contributor.author |
Muhammad Akram |
|
dc.contributor.author |
Mohammad Arfan |
|
dc.contributor.author |
Muhammad Qaisar |
|
dc.date.accessioned |
2023-01-20T09:08:17Z |
|
dc.date.available |
2023-01-20T09:08:17Z |
|
dc.date.issued |
2014-07-29 |
|
dc.identifier.citation |
Rauf, A., Khan, A., Uddin, N., Akram, M., Arfan, M., Uddin, G., & Qaisar, M. (2014). Preliminary phytochemical screening, antimicrobial and antioxidant activities of Euphorbia milli. Pakistan journal of pharmaceutical sciences, 27(4). |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/16468 |
|
dc.description.abstract |
Euphorbia milii is a Pakistani herb used for various infectious diseases. In this study we have carried out
phytochemical, antibacterial and antioxidant investigation of different extracts/fractions. Phytochemical studies showed the presence of cardiac glycosides, steroids/phytosterols, anthocyanin, proteins, terpenoids, flavonoids and tannins. Susceptibility testing by well diffusion assay of its chloroform and methanol fractions revealed good antimicrobial activity against Klebsiella pneumonia and Staph epidermis. Ethyl acetate fraction of roots also exhibited considerable antimicrobial activity against most of tested pathogens. Various fractions (Hexane, chloroform, methanol and water) of E. milii were screen for their antioxidant potential using DPPH radical scavenging assay at different concentrations among these, chloroform fraction exhibited good scavenging activity. The IR spectroscopy of the various extracts/fractions indicated the presence of OH, saturated CH stretching, C=C, C=O, NO2, C-N, Ar-O, C-O- and R-OStretching respectively. The findings provide helpful evidence for the use of E. milii in traditional medicines. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi |
en_US |
dc.subject |
Euphorbia milli |
en_US |
dc.subject |
antimicrobial activity |
en_US |
dc.subject |
DPPH radical scavenging assay |
en_US |
dc.subject |
IR spectroscopy |
en_US |
dc.title |
REPORT Preliminary phytochemical screening, antimicrobial and antioxidant activities of Euphorbia milli |
en_US |
dc.type |
Article |
en_US |