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PHYTOCHEMICAL AND ANTIMICROBIAL STUDIES OF SALVIA SPLENDENS SELLO

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dc.contributor.author KHAN, F. ZIA
dc.contributor.author M. ASIF SAEED
dc.date.accessioned 2023-01-20T09:32:38Z
dc.date.available 2023-01-20T09:32:38Z
dc.date.issued 1998-07-03
dc.identifier.citation Khan, F. Z., & Saeed, M. A. (1998). Phytochemical and antimicrobial studies of Salvia splendens Sello. Pakistan Journal of Pharmaceutical Sciences, 11(2), 13-21. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16531
dc.description.abstract The phytochemical investigation of antimicrobial agents from locally occurring Salvia splendens Sello, was carried out. Three common solvents i.e. petroleum ether (40-60%), chloroform and methanol were successively used for the extraction of antimicrobial principles from its various parts. Three major compounds (namely C1, C2, and C3) were isolated and purified from the active methanol extract of roots by column and thin layer chromatography. Gram positive bacteria (Bacillus pumilus, B. subtilis and Staphylococcus aureus), Gram negative bacteria (Proteus vulgaris, Escherichia coil and Pseudomonas aeruginosa) and a fungus (Candida albicans) was used to measure the zones of inhibition of these compounds by known method. One of the compound C1 gave larger zones than the other two isolated compounds (C2 and C3). An attempt was made to identify the nature of antimicrobial compounds by available spectral means. A possible structure-activity relationship of the potent antimicrobial compounds was discussed. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.title PHYTOCHEMICAL AND ANTIMICROBIAL STUDIES OF SALVIA SPLENDENS SELLO en_US
dc.type Article en_US


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