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HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ISONIAZID, PYRAZINAMIDE AND RIFAMPICIN IN PHARMACEUTICAL PREPARATIONSHIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ISONIAZID, PYRAZINAMIDE AND RIFAMPICIN IN PHARMACEUTICAL PREPARATIONS

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dc.contributor.author M.Y. KHUHAWAR
dc.contributor.author F.M.A. RIND
dc.date.accessioned 2023-01-20T09:33:44Z
dc.date.available 2023-01-20T09:33:44Z
dc.date.issued 1998-07-07
dc.identifier.citation Khuhawar, M. Y., & Rind, F. M. (1998). High performance liquid chromatographic determination of isoniazid, pyrazinamide and rifampicin in pharmaceutical preparations. Pakistan journal of pharmaceutical sciences, 11(2), 49-54. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16535
dc.description.abstract Isoniazid (IS) individually or in the presence of pyrazinamide and rifampicin has been determined by high performance liquid chromatography (HPLC) after derivatization with 6-methyl-2-pyridinecarboxaldehyde. Pyrazinamide and rifampicin separate completely from isoniazid derivative and are determined imultaneously. The chromatography is carried out from YMC-ODS column with elution with methanol: water: isopropanol: acetonitrile: sodium acetate (1 mM) 51:42:3:2:2: v/v/v/v/v/) with flow rate 1.7 ml/min and UV detection at 333 nm. The method is applied for the analysis of Isoniazid B.P Rambuzid and Myrene-p tablets. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.title HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ISONIAZID, PYRAZINAMIDE AND RIFAMPICIN IN PHARMACEUTICAL PREPARATIONSHIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ISONIAZID, PYRAZINAMIDE AND RIFAMPICIN IN PHARMACEUTICAL PREPARATIONS en_US
dc.type Article en_US


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