dc.contributor.author |
M.Y. KHUHAWAR |
|
dc.contributor.author |
F.M.A. RIND |
|
dc.date.accessioned |
2023-01-20T09:33:44Z |
|
dc.date.available |
2023-01-20T09:33:44Z |
|
dc.date.issued |
1998-07-07 |
|
dc.identifier.citation |
Khuhawar, M. Y., & Rind, F. M. (1998). High performance liquid chromatographic determination of isoniazid, pyrazinamide and rifampicin in pharmaceutical preparations. Pakistan journal of pharmaceutical sciences, 11(2), 49-54. |
en_US |
dc.identifier.issn |
1011-601X |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/16535 |
|
dc.description.abstract |
Isoniazid (IS) individually or in the presence of pyrazinamide and rifampicin has been determined by high performance liquid chromatography (HPLC) after derivatization with 6-methyl-2-pyridinecarboxaldehyde. Pyrazinamide and rifampicin separate completely from isoniazid derivative and are determined imultaneously. The chromatography is carried out from YMC-ODS column with elution with methanol: water: isopropanol:
acetonitrile: sodium acetate (1 mM) 51:42:3:2:2: v/v/v/v/v/) with flow rate 1.7 ml/min and UV detection at 333 nm. The method is applied for the analysis of Isoniazid B.P Rambuzid and Myrene-p tablets. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi |
en_US |
dc.title |
HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ISONIAZID, PYRAZINAMIDE AND RIFAMPICIN IN PHARMACEUTICAL PREPARATIONSHIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ISONIAZID, PYRAZINAMIDE AND RIFAMPICIN IN PHARMACEUTICAL PREPARATIONS |
en_US |
dc.type |
Article |
en_US |