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Browsing Issue No. 1 by Title

Browsing Issue No. 1 by Title

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  • Influence of Ibuprofen on the pharmacokinetics of isoniazid 
    M K Saleh; W A Malik; B Ahmad; K H Janbaz; M A Khan (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 1993-01-01)
    The influence of ibuprofcn (400 mg urally) on the pharmacokinetics of isoniazid (500 mg orally) was evaluated in healthy human subjects (n = 30). Subjects participated in a two way crossover trial, the first dosing condition ...
  • Serotonergic neurotransmission in the regulation of appetite: a receptor approach 
    D J Haleem (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 1993-01-12)
    Neurochemical research on brain 5-hydroxytryptamine (5-HT; serotonin) and feeding shows that rat brain serotonin metabolism is increased following ingestion of a carbohydrate rich diet to generate a neurochemical signal ...
  • Spectrophotometric determination of natural and substituted indoles by complexing with maleic anhydr1de 
    A N Manzar; W Hussain (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 1993-01-02)
    A spectrophotometric method has been developed for the quantitative determination of natural and ring-substituted indoles by complexing with maleic anhydride. The coloured complex exhibits absorbance maxima in the region ...
  • Stabiliiy of cyanocobalamin solutions insunlight and artificial light 
    I Ahmad; W Hussain (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 1993-01-04)
    A comparison of the degradation of cyanocobalamin (vitamin B(12)) solutions on exposure to sunlight and artificial light has been made using two concentrations, i.e. 950 mug/ml (corresponding to parenteral solutions) and ...
  • Stability of aminophylline 
    M Riaz; K H Ami (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 1993-01-06)
    The stability of aminophyline was studied in the presence of four tablet excipients (callu1ose starh, glucose and lactose) and nine intravenous fluids (water for injection, dextrose. 10% normal saline, dextrose normal ...
  • Stability of cyanocobalamin in parenteral preparations 
    I Ahmad; W Hussain (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 1993-01-08)
    The stability of seven commercial parenteral preparations of cyanocobalamin (vitamin B(12)) on storage under normal laboratory conditions for a period of twelve months has been studied using a two component spectrophotometric ...
  • Studies of the effect of anions (chloride, sulphate, nitrate, oxalate and acetate) on the pharmacological properties ofcobalt (ii) complexes with dithiooxamide-derived antibacterial agents 
    Z H Chohan; H Pervez (Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi, 1993-01-03)
    A number of cobalt (II) complexes with dithiooramide derived antibacterial agents having different anions i.e., chloride, sulphate, nitrate, oxalate and acetate have been synthesised, and the effect of anions on antibacterial ...

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