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A study on comparative efficacyof hypolipidemic drugs

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dc.contributor.author A Sher
dc.contributor.author A Ullah
dc.contributor.author A Mateen
dc.date.accessioned 2023-01-23T07:54:21Z
dc.date.available 2023-01-23T07:54:21Z
dc.date.issued 1995-01-01
dc.identifier.citation Sher, A., Ullah, A., & Mateen, A. (1995). A study on comparative efficacyof hypolipidemic drugs. Pakistan Journal of Pharmaceutical Sciences, 8(1), 1-9. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16607
dc.description.abstract A study was carried out on the comparative efficacy of Lopid, Mevacor, Bezalip and Lasona in sixteen hyperlipidemic subjects. All the subjects were on Lopid at least for the last 15 days. Lopid therapy was discontinued after determining blood lipid profile of the subjects on day zero (day of 1st contact). The subjects were divided into three groups and after a washout period of 15 days, they were given three different drugs for the next 15 days. Subjects in group a (6), b (5) and c (5) received Mevacor, Bezalip and lasona respectively. In the present study mevacor was found to be the most potent hypolipidemic drug in lowering blood cholesterol and Low density lipoprotein (LDL) while lopid was most effective in keeping blood Triglycerides (TG) and High density lipoproteins (HDL) level within the desired limits. Bezalip and Lasona were also sufficiently effective in changing blood lipid profile, but lasona showed a negligible effect on HDL rise as compared with Bezalip or any other drug used in this study. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.title A study on comparative efficacyof hypolipidemic drugs en_US
dc.type Article en_US


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