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Effect of cimetidine, ranitidine and tiotidine on plasma testosterone and luteinizing hormone levels in rats

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dc.contributor.author R T Mahmud
dc.contributor.author M S Akhter
dc.date.accessioned 2023-01-23T08:22:02Z
dc.date.available 2023-01-23T08:22:02Z
dc.date.issued 1994-01-06
dc.identifier.citation Mahmud, R. T., & Akhter, M. S. (1995). Effect of cimetidine, ranitidine and tiotidine on plasma testosterone and luteinizing hormone levels in rats. Pakistan Journal of Pharmaceutical Sciences, 8(1), 45-50. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16611
dc.description.abstract This investigation was carried out to study the comparative effects of cimetidine, ranitidine and tiotidine on the plasma levels of testosterone and luetinizing hormone under local conditions. The three H(2)-blocking drugs were injected to the adult male albino rats twice daily at the recommended therapeutic dose levels for six weeks. The data obtained showed that only tiotidine caused a significant (<0.05) increase in the level of testosterone. However, all the three drugs caused a significant rise in the levels of luteinizing hormone with the most active ranitidine administration. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.title Effect of cimetidine, ranitidine and tiotidine on plasma testosterone and luteinizing hormone levels in rats en_US
dc.type Article en_US


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