Haemolytic assay for the detection of adenylate cyclase toxin of Bordetella pertussis

dc.contributor.author	Y F Kazi
dc.contributor.author	R Parton
dc.contributor.author	B A Memon
dc.date.accessioned	2023-01-23T09:48:06Z
dc.date.available	2023-01-23T09:48:06Z
dc.date.issued	1994-07-06
dc.identifier.citation	Kazi, Y. F., Parton, R. O. G. E. R., & Memon, B. A. (1994). Haemolytic assay for the detection of adenylate cyclase toxin of Bordetella pertussis. Pak J Pharm Sci, 7(2), 55-9.	en_US
dc.identifier.issn	1011-601X
dc.identifier.uri	http://142.54.178.187:9060/xmlui/handle/123456789/16631
dc.description.abstract	The aim of this study was to device a simple, sensitive and convenient assay for the detection of toxicity of the Adenylate cyclase toxin (ACT), a newly recognized toxin of Bordetella pertussis. Haemolytic activity of ACT was analysed as an assay and sheep RBCs were found to be suitable to detect the toxic effect down to the dose of 6.25 nmol cAMP/min/ml enzymic activity applied. The haemolytic activity was found to be dose-dependent.	en_US
dc.language.iso	en	en_US
dc.publisher	Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi	en_US
dc.title	Haemolytic assay for the detection of adenylate cyclase toxin of Bordetella pertussis	en_US
dc.type	Article	en_US