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Changes in serum components induced by venoms of marine animals

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dc.contributor.author J M Alam
dc.contributor.author R Qasim
dc.date.accessioned 2023-01-23T10:17:11Z
dc.date.available 2023-01-23T10:17:11Z
dc.date.issued 1993-01-11
dc.identifier.citation Alam, J. M., & Qasim, R. (1993). Changes in serum components induced by venoms of marine animals. Pakistan Journal of Pharmaceutical Sciences, 6(1), 81-87. en_US
dc.identifier.issn 1011-601X
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/16647
dc.description.abstract Serum enzyme and chemical component levels were investigated in a rat model after experimental envenomation by venoms of coelentrate, Physalia species, four sea-snakes, Hydrophis spiralis, H. Cyanocinctus, H. Lapemoides and Lapemis curtus and a gastropod molluse Conus coronatus. The LD(50)s through i.v. route were found to be 4.2 mg/kg for Physalia, 0.4 mg/kg for H.spiralis 0.60 mg/kg for H.cyanocinctus, 0.60 mg/kg for H. lapemoides, 0.70 mg/kg for L.curtus and 2.9 mg/kg for C.coronatus. Marked elevation of serum enzyme levels was induced by sea-snake and Physalia venom while C.coronatus venom showed no significant change in serum levels. The results also indicate gross morphological changes in liver, spleen, gall bladder, lungs and heart by Physalia and sea snake venoms. en_US
dc.language.iso en en_US
dc.publisher Karachi: Faculty of Pharmacy & Pharmaceutical Sciences University of Karachi en_US
dc.title Changes in serum components induced by venoms of marine animals en_US
dc.type Article en_US


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