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EVALUATION OF THE ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES OF Cissampelos pareira L.

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dc.contributor.author M. Ajaib
dc.contributor.author F. Shafi
dc.contributor.author S.A. Mirza
dc.contributor.author Aziz-ul-Hassan
dc.contributor.author M.A. Iqbal
dc.date.accessioned 2023-03-14T06:01:50Z
dc.date.available 2023-03-14T06:01:50Z
dc.date.issued 2018-09-03
dc.identifier.citation Ajaib, M. (2018). EVALUATION OF THE ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES OF Cissampelos pareira L. Pakistan Journal of Science, 70(3). en_US
dc.identifier.issn 0300-9877
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/19049
dc.description.abstract In present study antimicrobial and antioxidant activities of leaf and stem ethanolic extracts of Cissampelos pareira were evaluated. Stem extract revealed good result as compared to leaf extract. The stem ethanolic extract exhibited good zone of inhibition against Escherichia coli and seudomonas aeruginosa with 13±0.33 mm and 14±0.58 mm diameter whereas minimum zone of inhibition was observed by leaf ethanolic extract against Bacillus subtilis and Staphylococcus aureus with 7±0.58 mm and 7±0.88 mm, respectively. The available antibiotics such as tetracycline, cefoperazone and erythromycin were used to compare all these results. The fungal strains i.e. Aspergillus oryzae and Aspergillus niger were used and significant results were recorded for stem ethanolic extract as compared with antifungal standard discs such as terbinafine and fungivin. The MIC assay was used for further analysis of leaf and stem extracts that inhibited bacterial and fungal growth. The antioxidant effect was evaluated by using 1,1-diphenyl-2picrylhydrazyl (DPPH) radical scavenging assay, total phenolic content and total flavonoid content. The stem extract of plant displayed good antioxidant potential as compared to the leaf extract. The % DPPH free radical scavenging activity was aximum of the stem extract (1.03±0.19 µg/ml). The maximum result of antioxidant activity was observed by total phenolic content i.e. 0.77±0.09 µg/ml at 1000 concentration. The ethanolic extract of stem had exhibited most elevated level of flavonoid content i.e. 0.70±0.06 µg/ml as compared to the leaf extract of C. pareira. en_US
dc.language.iso en en_US
dc.publisher Lahore: Pakistan Association For The Advancement Of Science en_US
dc.subject Cissampelos pareira en_US
dc.subject Antimicrobial en_US
dc.subject Antioxidant en_US
dc.subject Minimum Inhibitory Concentration. en_US
dc.title EVALUATION OF THE ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES OF Cissampelos pareira L. en_US
dc.type Article en_US


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