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COMPARATIVE ANALYSIS OF SOLVENT FREE, KHSO4 AND CE(SO4)2 CATALYZED MICROWAVE-ASSISTED SYNTHESIS OF 1, 3-DIAZACYCLOPENTA-2, 4-DIENES AND EVALUATION OF ITS ANTI-BACTERIAL ACTIVITY

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dc.contributor.author S. Ehsan
dc.contributor.author W. Akbar
dc.contributor.author S. Faisal
dc.contributor.author B. Khan
dc.date.accessioned 2023-03-14T06:03:29Z
dc.date.available 2023-03-14T06:03:29Z
dc.date.issued 2018-03-08
dc.identifier.citation Ehsan, S. (2018). COMPARATIVE ANALYSIS OF SOLVENT FREE, KHSO4 AND CE (SO4) 2 CATALYZED MICROWAVE-ASSISTED SYNTHESIS OF 1, 3-DIAZACYCLOPENTA-2, 4-DIENES AND EVALUATION OF ITS ANTI-BACTERIAL ACTIVITY. Pakistan Journal of Science, 70(1), 56-62. en_US
dc.identifier.issn 0300-9877
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/19064
dc.description.abstract The presented research demonstrated solvent free, microwave-assisted one-pot synthesis of derivatives of 1, 3-diazacyclopenta-2, 4-diene. The targeted moiety being a dynamic class of N-heterocycles had remained at the forefront of biological and medicinal chemistry throughout since they were important pharmacophores encompassing vast significant activities. Owing to the potency and wide applicability of this moiety, a diversity-oriented convergent synthesis through ulticomponent yclocondensation of dicarbonyl substrates with umerous aryl aldehydes and ammonium acetate was carried out by employing two active catalysts ndividually. In addition, the catalytic performance in the synthesis of the desired compounds was also ccessfully evaluated and the compounds were also tested again two bacterial strains. This protocol produced pure products in high yield within a short period having the enhancing features of easy work-up and a high degree of atom economy en_US
dc.language.iso en en_US
dc.publisher Lahore: Pakistan Association For The Advancement Of Science en_US
dc.subject One-pot synthesis en_US
dc.subject microwave-assisted synthesis en_US
dc.subject 1 en_US
dc.subject 3-diazacyclopenta-2, en_US
dc.subject 4-diene en_US
dc.subject multi-component reaction en_US
dc.subject cyclocondensation en_US
dc.title COMPARATIVE ANALYSIS OF SOLVENT FREE, KHSO4 AND CE(SO4)2 CATALYZED MICROWAVE-ASSISTED SYNTHESIS OF 1, 3-DIAZACYCLOPENTA-2, 4-DIENES AND EVALUATION OF ITS ANTI-BACTERIAL ACTIVITY en_US
dc.type Article en_US


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