dc.contributor.author |
S. Ehsan |
|
dc.contributor.author |
W. Akbar |
|
dc.contributor.author |
S. Faisal |
|
dc.contributor.author |
B. Khan |
|
dc.date.accessioned |
2023-03-14T06:03:29Z |
|
dc.date.available |
2023-03-14T06:03:29Z |
|
dc.date.issued |
2018-03-08 |
|
dc.identifier.citation |
Ehsan, S. (2018). COMPARATIVE ANALYSIS OF SOLVENT FREE, KHSO4 AND CE (SO4) 2 CATALYZED MICROWAVE-ASSISTED SYNTHESIS OF 1, 3-DIAZACYCLOPENTA-2, 4-DIENES AND EVALUATION OF ITS ANTI-BACTERIAL ACTIVITY. Pakistan Journal of Science, 70(1), 56-62. |
en_US |
dc.identifier.issn |
0300-9877 |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/19064 |
|
dc.description.abstract |
The presented research demonstrated solvent free, microwave-assisted one-pot synthesis of derivatives of 1, 3-diazacyclopenta-2, 4-diene. The targeted moiety being a dynamic class of N-heterocycles had remained at the forefront of biological and medicinal chemistry throughout since they were important pharmacophores encompassing vast significant activities. Owing to the potency and wide applicability of this moiety, a diversity-oriented convergent synthesis through ulticomponent yclocondensation of dicarbonyl substrates with umerous aryl aldehydes and ammonium acetate was carried out by employing two active catalysts ndividually. In addition, the catalytic performance in the synthesis of the desired compounds was also ccessfully evaluated and the compounds were also tested again two bacterial strains. This protocol produced pure products in high yield within a short period having the enhancing features of easy work-up and a high degree of atom economy |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Lahore: Pakistan Association For The Advancement Of Science |
en_US |
dc.subject |
One-pot synthesis |
en_US |
dc.subject |
microwave-assisted synthesis |
en_US |
dc.subject |
1 |
en_US |
dc.subject |
3-diazacyclopenta-2, |
en_US |
dc.subject |
4-diene |
en_US |
dc.subject |
multi-component reaction |
en_US |
dc.subject |
cyclocondensation |
en_US |
dc.title |
COMPARATIVE ANALYSIS OF SOLVENT FREE, KHSO4 AND CE(SO4)2 CATALYZED MICROWAVE-ASSISTED SYNTHESIS OF 1, 3-DIAZACYCLOPENTA-2, 4-DIENES AND EVALUATION OF ITS ANTI-BACTERIAL ACTIVITY |
en_US |
dc.type |
Article |
en_US |