Synthesis of N-Methylbutobarbitone-N-(methyl 2,3, 4-tri-O-acetyl-B-D-glucuronide) under Phase Transfer catalysed condition

Abstract

N-Methylbutobarbitone-N-glucuronic acid (protected) was successfully synthesized by a phase transfer catalysed reaction; it was then characterized by proton NMR and mass spectrometry (EI), for use in investigating the human metabolism of butobarbitone.