dc.contributor.author |
HAFIZ A. BARI INDHAR |
|
dc.contributor.author |
A. W. K. KHANZADA |
|
dc.date.accessioned |
2023-08-28T09:45:20Z |
|
dc.date.available |
2023-08-28T09:45:20Z |
|
dc.date.issued |
2000-03-01 |
|
dc.identifier.citation |
Bari Indhar, H. A., & Khanzada, A. W. K. (2000). Determination of dissociation constants and thermodynamic parameters of 8-aminoquinoline by potentiometry in aqueous and mixed organic-water solvent systems. Journal of the Chemical Society of Pakistan, 22, 1-5. |
en_US |
dc.identifier.issn |
0253-5106 |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/19564 |
|
dc.description.abstract |
The dissociation constant (pKa) and thermodynamic parameters (△G) of 8-aminoquinoline are determined in aqueous and in mixed organic-water (dioxane, EtOH and MeOH) solvent systems. It is observed that ionization constant of 8-aminoquinoline in aqueous system increases with the increase of temperature. The curve is a parabolic one. It is to be noted that pKa values of this compound are lower than those of quinoline and some of its amino derivatives. For mixed organic-water solvent systems pKa M and pKaT values versus percent composition decrease slowly with increase in percent of EtOH, MeOH and dioxane. The curve of the pK. versus percent composition is a distorted parabola.The data have been obtained potentiometrically by titrating aqueous 8-aminoquinoline solution with hydrochloric acid. The values of dissociation constant were obtained from these data by a computer program written in GW-BASIC. From pKa values Gibb's free energies (△G) have also been calculated. |
en_US |
dc.description.sponsorship |
The chemical society of Pakistan is an approved society from the PSF |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
The Chemical Society Of Pakistan |
en_US |
dc.title |
Determination of Dissociation Constants and Thermodynamic Parameters of 8-Aminoquinoline by Potentiometry in Aqueous and Mixed Organic-Water Solvent Systems |
en_US |
dc.type |
Article |
en_US |