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Assessment of Bioactivity of Cassiafistula Using Bombyx mori Lethality Assay

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dc.contributor.author MUHAMMAD ASHFAQ
dc.contributor.author HANIF, MUHAMMAD ASIF
dc.contributor.author JAMIL, MUHAMMAD SALMAN
dc.date.accessioned 2023-09-18T09:31:21Z
dc.date.available 2023-09-18T09:31:21Z
dc.date.issued 2009-10-20
dc.identifier.citation Ashfaq, M. (2009). Assessment of bioactivity of cassia fistula using bombyx mori lethality assay. Journal of the Chemical Society of Pakistan, 31(5), 772-776. en_US
dc.identifier.issn 0253-5106
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/19639
dc.description.abstract In recent times, focus on plant research has increased all over the world and a large body of evidence is being collected to evaluate immense potential of medicinal plants used in various traditional systems. In this regard, the present study was conducted to evaluate the bioactivity of a commonly used medicinal plant Cassia fistula against newly selected Bombyx mori (silkworm) larvae. C. fistula pods were extracted using water, methanol, ethanol, hydro-methanol (I: l) and hydro-ethanol (l : I) and were assayed for their activity against Bombyx mori. Methanol extract of C. fistula at concentration of 100 mg/L killed half (LCM)) of Bomyx mori larvae under study. Bonwx mori LC50 for other C. fistula extracts were 400 mg/L for ethanol and hydro-methanol, 800 mg/L for hydro-ethanol and 1600 mg/L for aqueous extract. From the results of the present study it can be concluded that Bombyx mori lethality bioassay can be considered a usetill preliminary tool for plant extract toxicity evaluation. The main objectives of the present study was to develop a new and simple assay to evaluate claims from traditional, tribal and advanced medicinal lore to suggest directions for future clinical research and commercial importance that could be carried out by local investigators in developing regions en_US
dc.description.sponsorship The chemical society of Pakistan is an approved society from the PSF. en_US
dc.language.iso en en_US
dc.publisher HEJ Research Institute of Chemistry, University of Karachi, Karachi. en_US
dc.title Assessment of Bioactivity of Cassiafistula Using Bombyx mori Lethality Assay en_US
dc.type Article en_US


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