PASTIC Dspace Repository

Effect of L-Ascorbic Acid on the Formulation and Characterization of a Multiple Emulsion from Paraffin Oil

Show simple item record

dc.contributor.author NAVEED AKHTAR
dc.contributor.author NOSHEEN ZULFIQAR
dc.contributor.author GULFISHAN
dc.contributor.author MAHMOOD AHMED
dc.contributor.author HAJI M
dc.contributor.author SHOAIB KHAN
dc.contributor.author TARIQ SAEED
dc.date.accessioned 2023-10-02T07:00:46Z
dc.date.available 2023-10-02T07:00:46Z
dc.date.issued 2010-12-05
dc.identifier.citation AKHTER, N., KHAN, H. M. S., ZULFIQAR, N., FISHAN, G., AHMED, M., & Saeed, T. (2010). Effect of L-Ascorbic Acid on the Formulation and Characterization of a Multiple Emulsion from Paraffin Oil. Journal of The Chemical Society of Pakistan, 32(6), 724. en_US
dc.identifier.issn 0253-5106
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/19747
dc.description.abstract Multiple emulsions contain at least three phases. The material entrapped in internal phase is released slowly and thus its effects can be prolonged. The other benefit of multiple emulsions is protection of material entrapped in internal phase. The purpose of the study was to prepare a stable multiple emulsion containing a skin antiaging agent L-Ascorbic acid (vitamin C) using paraffin oil. L-Ascorbic acid, which is a very unstable ingredient and is decomposed in the presence of oxygen, in a concentration of 2% was entrapped in the inner most aqueous phase of w/o/w multiple emulsion. Formulation of multiple emulsion was stored at different accelrated conditions i.e. 8 ºC, 25 ºC, 40 ºC and 40 ºC+75% RH (Relativ Humidity) for 28 days to predict the stability of formulation. Formulation was found to be stable at lower temperatures for a given period of time and no phase sepration was observed in any sample. Different parameters like pH, globule size, electrical conductivity and effects of centrifugation were studied for a period of 28 days to confirm the stability of multiple emulsion. It was found that there was no significant change in globule sizes in any sample kept at most of the conditions. Significant changes in both pH and conductivity were observed in the samples of formulation kept at 8 ºC. Insignificant changes both in pH and electrical conductivity were observed in samples of formulation kept at 40 ºC and 40 ºC + 75%RH conditions throughout study period. The data obtained was evaluated statistically using two way ANOVA (Analysis of Variance) and LSD (Least Significant Difference) tests. en_US
dc.description.sponsorship The chemical society of Pakistan is an approved society from the PSF. en_US
dc.language.iso en en_US
dc.publisher Karachi: The Chemical Society of Pakistan en_US
dc.title Effect of L-Ascorbic Acid on the Formulation and Characterization of a Multiple Emulsion from Paraffin Oil en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account