Antileishmanial Steroidal Alkaloids from Roots of Sarcococca coriacea

dc.contributor.author	MUHAMMAD IQBAL, CHOUDHARY
dc.contributor.author	ACHYUT ADHIKARI
dc.contributor.author	SAMREEN
dc.contributor.author	ATTA-UR-RAHMAN
dc.date.accessioned	2023-10-03T05:26:15Z
dc.date.available	2023-10-03T05:26:15Z
dc.date.issued	2010-12-20
dc.identifier.citation	Choudhary, M. I., Adhikari, A., & Rahman, A. (2010). Antileishmanial steroidal alkaloids from roots of Sarcococca coriacea. J Chem Soc Pak, 32, 799-802.	en_US
dc.identifier.issn	0253-5106
dc.identifier.uri	http://142.54.178.187:9060/xmlui/handle/123456789/19764
dc.description.abstract	Bio-assay guided isolation of secondary metabolites from the plant Sarcococca coriacea (Hook. f.) yielded two steroidal alkaloids, alkaloid C (1) and iso-N-formylchonemorphine (2). The structures of compounds were identified by different spectroscopic techniques. Compounds 1 and 2 showed significant anti-leishmanial activities IC₅₀ = 13.20 ± 0.05 µM and 24.76 ± 0.01 µM, respectively, in comparison with standard drugs pentamidine IC₅₀ = 8.58 ± 0.04 µM and amphotericin B IC₅₀ = 0.31 ± 0.05 µM.	en_US
dc.description.sponsorship	The chemical society of Pakistan is an approved society from the PSF.	en_US
dc.language.iso	en	en_US
dc.publisher	HEJ Research Institute of Chemistry, University of Karachi, Karachi.	en_US
dc.title	Antileishmanial Steroidal Alkaloids from Roots of Sarcococca coriacea	en_US
dc.type	Article	en_US