Abstract:
During the search for bioactive constituents from different parts of Aegle marmelos (Rutaceae), the ethanol soluble portion of fresh unripe fruits yielded two known amides named aegeline (1) and 2-O-methyl aegeline (2), and five known coumarins named xanthotoxol (3), alloimperatorin (4), marmesin (5), marmin (6), 7′-O-methylmarmin (7). Structures of 1-7 were elucidated with the aid of spectroscopic techniques. All the isolated constituents (1-7) were tested for urease inhibition. allo-Imperatorin was found the most potent among the all tested samples with the IC₅₀ value 27.5 µM.
