dc.contributor.author |
ALI, MUHAMMAD SHAIQ |
|
dc.contributor.author |
GHAFOOR AHMED |
|
dc.contributor.author |
PERVEZ, MUHAMMAD KASHIF |
|
dc.contributor.author |
MEHREEN LATEEF |
|
dc.contributor.author |
NIGHAT AFZA |
|
dc.contributor.author |
LUBNA IQBAL |
|
dc.date.accessioned |
2023-10-06T05:51:23Z |
|
dc.date.available |
2023-10-06T05:51:23Z |
|
dc.date.issued |
2011-12-20 |
|
dc.identifier.citation |
Ali, M. S., Ahmed, G., Pervez, M. K., Lateef, M., Afza, N., & Iqbal, L. (2011). allo-Imperatorin: A potent urease inhibitor from fresh unripe fruits of Aegle marmelos (Rutaceae). Journal of the Chemical Society of Pakistan, 33(6), 960-964. |
en_US |
dc.identifier.issn |
0253-5106 |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/19806 |
|
dc.description.abstract |
During the search for bioactive constituents from different parts of Aegle marmelos (Rutaceae), the ethanol soluble portion of fresh unripe fruits yielded two known amides named aegeline (1) and 2-O-methyl aegeline (2), and five known coumarins named xanthotoxol (3), alloimperatorin (4), marmesin (5), marmin (6), 7′-O-methylmarmin (7). Structures of 1-7 were elucidated with the aid of spectroscopic techniques. All the isolated constituents (1-7) were tested for urease inhibition. allo-Imperatorin was found the most potent among the all tested samples with the IC₅₀ value 27.5 µM. |
en_US |
dc.description.sponsorship |
The chemical society of Pakistan is an approved society from the PSF. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
HEJ Research Institute of Chemistry, University of Karachi, Karachi. |
en_US |
dc.title |
allo-Imperatorin: A Potent Urease Inhibitor from Fresh Unripe Fruits of Aegle marmelos (Rutaceae) |
en_US |
dc.type |
Article |
en_US |