Sensitivity of Cells Towards Streptolysin S (SLS)

dc.contributor.author	BADARUDDIN A. MEMON
dc.date.accessioned	2023-10-27T06:14:34Z
dc.date.available	2023-10-27T06:14:34Z
dc.date.issued	2010-04-12
dc.identifier.citation	MEMON, B. R. A. (2010). Sensitivity of Cells Towards Streptolysin S (SIS). J. Chem. Soc. Pak, 32(2), 95.	en_US
dc.identifier.issn	0253-5106
dc.identifier.uri	http://142.54.178.187:9060/xmlui/handle/123456789/19888
dc.description.abstract	Streptolysin S (SLS) produced by group A Streptococcus (GAS) is very potent membrane-damaging agent and lyses a wide variety of living cells and organelles. This study is about the comparison between the relative sensitivity of sheep red blood cells (haemolytic assay) and that of rabbit peritoneal neutrophils (chemiluminescence assay) towards the purified SLS. Purified SLS, at concentrations of between 8000 HU/ml and 256 HU/ml, when added directly to FMLP-induced rabbit PMNs, caused inhibition of the PMNs chemiluminescence response. This study concludes that on a cell basis, sheep red blood cells are 1.2x105 fold more sensitive to SLS than PMNs.	en_US
dc.description.sponsorship	The chemical society of Pakistan is an approved society from the PSF.	en_US
dc.language.iso	en	en_US
dc.publisher	HEJ Research Institute of Chemistry, University of Karachi, Karachi.	en_US
dc.title	Sensitivity of Cells Towards Streptolysin S (SLS)	en_US
dc.type	Article	en_US