dc.contributor.author |
MUSTAFA ER |
|
dc.contributor.author |
NECDFT COSKUN |
|
dc.date.accessioned |
2023-10-31T04:24:25Z |
|
dc.date.available |
2023-10-31T04:24:25Z |
|
dc.date.issued |
2010-04-13 |
|
dc.identifier.citation |
Er, M. (2010). Substituent Effect on the Asymmetric Induction with (1R, 2S, 5R)-and (1S, 2R, 5S)-menthol Auxiliaries. |
en_US |
dc.identifier.issn |
0253-5106 |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/19889 |
|
dc.description.abstract |
Substituted benzaldehydes reacts in cis-diastereoselective manner with menthyl haloacetates in the presence of phase transfer catalyst and a base in THF at room temperature to give the corresponding 3-aryloxirane-2-carboxylates (2/3a-h) in moderate to high yields. The magnitude of asymmetric induction in the latter reaction was quantified by a Hammett type equation log(2/3)X = rsI + log(2/3)X=H. The stereochemistry of compounds 2 and 3 was elucidated by correlation with (4S,5R)-2,4-diphenyl-4,5-dihydrooxazole-5-carboxylic acid (+)-8 as well as its enantiomer (-)-8. |
en_US |
dc.description.sponsorship |
The chemical society of Pakistan is an approved society from the PSF. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
HEJ Research Institute of Chemistry, University of Karachi, Karachi. |
en_US |
dc.title |
Substituent Effect on the Asymmetric Induction with (1R,2S,5R)-and (1S,2R,5S)-menthol Auxiliaries |
en_US |
dc.type |
Article |
en_US |