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Compettition of Aluminium on Iron Binding Site in the Biological System

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dc.contributor.author FOUZIA SULTANA REHMANI
dc.contributor.author ABDULAHAD SHAFIQUE
dc.contributor.author ASADULLAH SHAFIQUE
dc.contributor.author SHERAZ AHMAD KHAN
dc.contributor.author SABAHAT AMBREEN
dc.contributor.author MUHAMMAD INAM-UL-HAQ
dc.contributor.author MUHAMMAD RASHID
dc.contributor.author SYED SAMMAR ABBAS
dc.date.accessioned 2023-11-07T05:10:24Z
dc.date.available 2023-11-07T05:10:24Z
dc.date.issued 2010-08-20
dc.identifier.citation Rehmani, F. S. (2010). Compettition of Aluminium on Iron Binding Site in the Biological System. Journal of the Chemical Society of Pakistan, 32(6), 467. en_US
dc.identifier.issn 0253-5106
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/19922
dc.description.abstract Aluminum toxicity has been recognized in many ways, when exposure to heavy metals is prolonged, renal function is limited or a previously accumulated bone burden is released in stress and illness. Aluminum is generally found in +3 oxidation state, so sometimes it competes for the binding sites of Fe(III) in the biological system. If the concentration of Aluminum exceeds above the normal, it inhibits the absorption of Iron and Iron deficiency leads to diseases such as Parkinson's and Alzheimer. The complex formations of Al(III) and Fe(III) with salicylic hydroxamate were studied potentiometrically at different temperatures and data were subjected to computer programs. The stability constant (log β) values and thermodynamic stabilities were calculated. It was found that salicylic hydroxamate forms 1:1 complex at pH 3 and 1: 2 complex at pH 4 with Al(III) and Fe(III), respectively. The stability constant (log β) and thermodynamic stabilities of Al(III) salicylic hydroxamate complexes are close to Fe(III) salicylic hydroxamate complexes. en_US
dc.description.sponsorship The chemical society of Pakistan is an approved society from the PSF. en_US
dc.language.iso en en_US
dc.publisher HEJ Research Institute of Chemistry, University of Karachi, Karachi. en_US
dc.title Compettition of Aluminium on Iron Binding Site in the Biological System en_US
dc.type Article en_US


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