PASTIC Dspace Repository

Gas Chromatographic Analysis of Tranexamic Acid in Pharmaceutical Preparation Using Ethyl Chloroformate as Derivatizing Reagent

Show simple item record

dc.contributor.author KULSOOM UBEDULLAH ABBASI
dc.contributor.author MUHAMMAD YAR KHUHAWAR
dc.contributor.author MUHAMMAD IQBAL BHANGER
dc.date.accessioned 2023-11-30T04:21:35Z
dc.date.available 2023-11-30T04:21:35Z
dc.date.issued 2010-06-06
dc.identifier.citation Abbasi, K. U., Khuhawar, M. Y., & Bhanger, M. I. (2011). Gas Chromatographic Analysis of Tranexamic Acid in Pharmaceutical Preparation Using Ethyl Chloroformate as Derivatizing Reagent. Journal of the Chemical Society of Pakistan, 32(6), 301. en_US
dc.identifier.issn 0253-5106
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/19979
dc.description.abstract Ethyl chloroformate (ECF) has been used as derivatizing agent for gas chromatographic (GC) determination of tranexamic acid (TA). The elution was from the column HP-5 (30 m x 0.32 mm i.d.) connected with flame ionization detection (FID). Linear calibration curves were obtained with 2-50 ng TA injection on the column. Aminocaproic acid (ACA) when present together with TA could also be separated and determined simultaneously. TA was determined from pharmaceutical preparation. Relative standard deviation (RSD) for analysis was observed within 0.1-0.4 %. The pharmaceutical additives and number of amino acid when present together with TA did not affect the determination of TA. en_US
dc.description.sponsorship The chemical society of Pakistan is an approved society from the PSF. en_US
dc.language.iso en_US en_US
dc.publisher HEJ Research Institute of Chemistry, University of Karachi, Karachi. en_US
dc.title Gas Chromatographic Analysis of Tranexamic Acid in Pharmaceutical Preparation Using Ethyl Chloroformate as Derivatizing Reagent en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account