dc.contributor.author |
XIAO YU-MEI |
|
dc.contributor.author |
WANG JIAN |
|
dc.contributor.author |
WANG MING-AN |
|
dc.contributor.author |
LIU JI-PING |
|
dc.contributor.author |
YUAN HUI-ZHU |
|
dc.contributor.author |
QIN ZHAO-HAI |
|
dc.date.accessioned |
2023-12-01T04:41:09Z |
|
dc.date.available |
2023-12-01T04:41:09Z |
|
dc.date.issued |
2010-06-17 |
|
dc.identifier.citation |
AN, W. M., PING, L. J., Hai, Q. Z., JIAN, W., ZHU, Y. H., & MEI, X. Y. (2011). Study on the inclusion complexes of flumorph and dimethomorph with β-cyclodextrin to improve fungicide formulation. Journal of the Chemical Society of Pakistan, 32(6), 363. |
en_US |
dc.identifier.issn |
0253-5106 |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/19990 |
|
dc.description.abstract |
The β-Cyclodextrin (β-CD) complexes of Flumorph and Dimethomorph have been investigated quantitatively by UV measurement. The results showed that the 1:1 inclusion complexes were formed and the formation constants reduced with elevation of temperature. Thermodynamic parameters of the inclusion reaction (ΔH?ΔS?ΔG) were all negative,which suggested that the interaction process between β-CD and the two fungicides were spontaneous, driven by entropy changes of inclusion reaction. Two-dimensional (2D) ROESY NMR experiments were performed to identify the binding geometry of inclusion complex. Both of Z and E isomers of Flumorph formed complexes with β-CD, while only the Z-isomer of Dimethomorph formed complex with β-CD, and the phenyl ring containing fluorine or chlorine atom entered into the cavity of β-CD through the wider rim. Phase-solubility experiments demonstrated that the water-solubility of the two fungicides enhanced in the presence of β-CD. The preliminary bioassay testified that the complexes improved the fungicidal activity. The present study provided a promising outlook for developing water-based formulation of Flumorph and Dimethomorph, increasing its efficacy and improving its formulation. |
en_US |
dc.description.sponsorship |
The chemical society of Pakistan is an approved society from the PSF. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
HEJ Research Institute of Chemistry, University of Karachi, Karachi. |
en_US |
dc.title |
STUDY ON THE INCLUSION COMPLEXES OF FLUMORPH AND DIMETHOMORPH WITH Β-CYCLODEXTRIN TO IMPROVE FUNGICIDE FORMULATION |
en_US |
dc.type |
Article |
en_US |