dc.contributor.author |
SALEHA SULEMAN KHAN |
|
dc.contributor.author |
AJMAL KHAN |
|
dc.contributor.author |
BISHNU P. MARASINI |
|
dc.contributor.author |
NIKHAT SABA |
|
dc.contributor.author |
VIQAR UDDIN AHMAD |
|
dc.contributor.author |
MEHRDAD IRANSHAHI |
|
dc.contributor.author |
SEYYED TAHMINEH HOSSEINI |
|
dc.contributor.author |
MUHAMMAD IQBAL CHOUDHARY |
|
dc.date.accessioned |
2023-12-15T06:45:16Z |
|
dc.date.available |
2023-12-15T06:45:16Z |
|
dc.date.issued |
2012-06-20 |
|
dc.identifier.citation |
Khan, S. S., Khan, A., Marasini, B. P., Saba, N., Ahmad, V. U., Iranshani, M., ... & Choudhary, M. I. (2012). (alpha)-Chymotrypsin and Urease Inhibitory Activity of Diversolides C, D and E from the Roots of Ferula Diversivittata. Journal of the Chemical Society of Pakistan, 34(3). |
en_US |
dc.identifier.issn |
0253-5106 |
|
dc.identifier.uri |
http://142.54.178.187:9060/xmlui/handle/123456789/20026 |
|
dc.description.abstract |
Sesquiterpene lactone derivatives, diversolides-C (giferolide) (1), -D (malafilin) (2), and -E (fegvolide) (3), isolated from the roots of Ferula diversivittata, Regel. & Schmalh, were evaluated for α-chymotrypsin and urease inhibition activities. Diversolide-E (3) was found to be a moderate inhibitor against both enzymes while all others were found to be inactive. The IC₁₅₀ ± SEM values of 3 were 388.2 ± 1.7 µM, and 116.0 ± 4.8 µM for α-chymotrypsin and urease, respectively. |
en_US |
dc.description.sponsorship |
The chemical society of Pakistan is an approved society from the PSF. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
HEJ Research Institute of Chemistry, University of Karachi, Karachi. |
en_US |
dc.subject |
Ferula diversivittata |
en_US |
dc.subject |
α-chymotrypsin |
en_US |
dc.subject |
, urease, diversolide |
en_US |
dc.title |
Α-Chymotrypsin and Urease Inhibitory Activity of Diversolides C, D and E from the Roots of Ferula Diversivittata |
en_US |
dc.type |
Article |
en_US |