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PHYTOCHEMICAL AND BIOLOGICAL STUDIES OF EUPHORBIA SERPENS, EUPHORBIA GRANULATA (EUPHORBIACEAE) AND VERNONIA CINERASCENS (COMPOSITAE)

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dc.contributor.author Ahmad, Irshad
dc.date.accessioned 2017-12-26T07:55:29Z
dc.date.accessioned 2020-04-09T16:36:57Z
dc.date.available 2020-04-09T16:36:57Z
dc.date.issued 2009
dc.identifier.uri http://142.54.178.187:9060/xmlui/handle/123456789/2783
dc.description.abstract The present research work emphasis on the biological and Phytochemical studies of the medicinal plants Vernonia cinerascens (Compositae), Euphorbia granulata and Euphorbia serpens (Euphorbiaceae). Dichloromethane and methanol extracts of the different parts of Vernonia cinerascens, Euphorbia granulata and Euphorbia serpens were prepared. These extracts were subjected to a battery of biological screening and it was observed that dichloromethane extracts of Vernonia cinerascens roots and that of Euphorbia granulata whole plant exhibited significant antifungal activity against Microsporum canis. Microsporum canis is responsible for tinea capitis and tinea corporis. Methanol extract of Vernonia cinerascens also showed significant antifungal activity against Fusarium solani. Fusarium solani is a pathogen responsible for fungal infections in plant and human. Dichloromethane and methanol extracts of Euphorbia serpens exhibited moderate antifungal activity against Aspergillus flavus. Methanol extracts of Vernonia cinerascens and Euphorbia serpens showed antioxidant activity. All the extracts have dose dependent spasmolytic activity. Dichloromethane extract of Vernonia cinerascens root was subjected for Phytochemical investigations and afforded a new monoterpene, (3β-acetoxy-5α-angeloyloxy-7-deoxy-carvotacetone). Methanol extract of the same plant when subjected for isolation offered a new flavone (5,4'-dihydroxy-7-(4-hydroxybenzoyl)-3'-methoxyflavone) and eight known compounds, namely, 2-hydroxy-3-methoxy-5-(2′-propenyl)-phenol, vanillic acid, isoferulic acid, caffeic acid, methyl gallate, uridine, 3'-methylquercetin and quercetin. en_US
dc.description.sponsorship Higher Education Commission, Pakistan en_US
dc.language.iso en en_US
dc.publisher BAHAUDDIN ZAKARIYA UNIVERSITY MULTAN, PAKISTAN en_US
dc.subject Applied Sciences en_US
dc.title PHYTOCHEMICAL AND BIOLOGICAL STUDIES OF EUPHORBIA SERPENS, EUPHORBIA GRANULATA (EUPHORBIACEAE) AND VERNONIA CINERASCENS (COMPOSITAE) en_US
dc.type Thesis en_US


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