Abstract:
This research project had three aspects,
1. Synthesis of novel dyes,
2. Assessing their applications i.e. fastness properties etc.
3. Testing the synthesised dyes for their mutagenicity.
Synthesis and evaluation of azo disperse dyes was done while using
different
aminoflavones
(4 ́-Aminoflavone,
3 ́-Aminoflavone
and
6-
Aminoflavone), and coumarins (like 6-Amino-4-methylcoumarin and 4-Methyl-
7-hydroxy-coumarin).
Dyes (16-75) have been synthesized by coupling the synthesized
intermediates with the substituted aniline (1-10) as well as the naphthalene
based couplers (11-15). The characterization of the dyes was done by
Infrared, 1H-NMR, Mass Spectrometry,
13
C-NMR and Elemental analysis.
Diazotization of the different heterocyclic amines (1a-10a).was carried out and
the 4-Methyl-7-hydroxycoumarin was used as coupler to yield the dyes (76-
85).
The synthesised dyes were applied on the polyester fabric and it
proved to be effective as they gave good fastness properties. The dyes
obtained had good fast colours ranging from orange to purple. Some of the
synthesised dyes (16, 17, 20, 23, 24, 28) were also applied on the Nylon-lycra
fabric and it gave good dyeing as well as good to moderate fastness
properties. The yield of the dyes obtained was from 65-83 %.
All the synthesised dyes were evaluated for their mutagenicity by
undergoing standard Ames test. This was performed by using the Salmonella
strains (TA 98 and TA 100) with and without S9 activation.
The results of these mutagenicity results showed that almost all the
dyes proved to be negative in the Ames test except the dyes having free
amino group which can be attributed to be cause of their mutagenicity. The
presence of the free amino group made these dyes more prone to be
mutagenic as compared to the other dyes.
